Description
Precautions and warnings
Renal dysfunction, low phosphate diet, prolonged use.
Side-effects
Diarrhoea
Constipation
Nausea
Vomiting.
Drug Interactions
Aluminium Hydroxide: Absorption is improved when combined with citrates or ascorbic acid. Allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine, phenytoin, phenothia.
Tetracyclines and biphosphonates are less absorbed when magnesium hydroxide is present. After about 2 hours, these and other medications should be administered separately.
Contraindications
Hypophosphataemia.
Mode of actions
By neutralizing the HCl in the stomach, aluminum hydroxide forms aluminum chloride salt and water.
Magnesium hydroxide stimulates peristaltic activity, resulting in osmotic fluid retention and bowel evacuation. It also decreases stomach acid by forming Mg chloride when it reacts with hydrochloric acid.
Dosage & Administration
Chew 1-2 tablets after meals and at bedtime as needed (up to 4 times a day) or as directed by a doctor. For best results, drink a half glass of water or other liquid after each dose. Do not take more than 16 tablets in 24 hours
Pregnancy & Lactation
FDA has not yet classified this medicine into a specified pregnancy category. Although there is no enough evidence that taking this medicine during you are pregnant is harmful.
Discuss with your doctor if you are trying to get pregnant while taking this medicine too.
If you do become pregnant while you are taking this medicine, you should continue to take it and contact with your doctors as quickly as possible. They can assist you to decide whether or not to keep taking this medicine. If you abandon taking this medicine and become sick, this would be more pernicious to your child than staying on the medication.
There is no specific information about whether this medicine is passed on to the baby through breast milk. During this medication, if your baby becomes very sleepy, restless, fatigued, exhibit feeding problems, stop breastfeeding and talk to your doctors very quickly.
